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Price / sales at other companies

Bristol-Myers Squibb logo
Bristol-Myers SquibbBMY
2.6×-0.1×
Eli Lilly logo
Eli LillyLLY
11.4×-3.8×
Pfizer logo
PfizerPFE
2.5×+0.2×
Johnson & Johnson logo
Johnson & JohnsonJNJ
6.1×+1.6×
Merck & Co. logo
Merck & Co.MRK
4.5×+1.0×
AbbVie logo
AbbVieABBV
6.1×-0.3×

Other financials

Income statement

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Revenue-
Operating income-$45.6M+14.8%
Net income-$69.0M-54.1%
EPS (diluted)-$0.74-23.3%

Balance sheet

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Cash & equivalents$97.2M+100%
Total debt$4.3M-9.6%
Total equity$670.8M+39.0%
Total assets$764.0M+34.1%

Cash flow

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Operating cash flow-$57.4M-40.0%
CapEx-
Free cash flow-$39.4M-26.8%

Valuation

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Market cap$7.67B+307%

Profitability

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Operating margin-39,428.9%-49,795pp
Net margin-52,939.7%-61,871pp
FCF margin-3,442.8%-3,807pp

Returns & leverage

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Return on equity-31.1%-10.7pp
Debt / equity0.1×+0.1×
Current ratio+0.9×

Where this comes from

Calculated from Spyre Therapeutics, Inc.’s reported figures.

Based on the most recent quarter.

The official record: Spyre Therapeutics, Inc.’s 10-Q, filed May 8, 2025, on SEC EDGAR. View the filing →

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Questions, answered.

What is Spyre Therapeutics, Inc.'s price / sales?
Spyre Therapeutics, Inc. (SYRE) reported price / sales of 1,993× in Q1 2024.
How has Spyre Therapeutics, Inc.'s price / sales changed year-over-year?
Spyre Therapeutics, Inc.'s price / sales increased by 8393.8% year-over-year, from 23.5× to 1,993×.
What is the long-term trend for Spyre Therapeutics, Inc.'s price / sales?
Over 2 years (2021 to 2023), Spyre Therapeutics, Inc.'s price / sales has grown at a 623.2% compound annual growth rate (CAGR), from 16.7× to 874.9×.
What does price / sales mean?
How many dollars investors pay for each dollar of the company's annual sales.
How do you interpret price / sales?
Useful when earnings are negative or volatile (e.g. early-stage or cyclical firms). Only comparable across companies with similar margins — a sales dollar is worth more at a high-margin business.
How does price / sales compare across companies?
Best compared within a margin cohort; a software P/S and a retailer P/S are not directly comparable.