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Septerna, Inc. SEPN Q2 2025 earnings

Reported August 11, 2025 · Before market open

Revenue$119.0KMiss by $4.9M
EPS-$0.56Miss by $0.51
Revenue estimate$5.0M
EPS estimate-$0.05

Next report

Nov 9, 2026 (in 2 months)
Revenue estimate$20.8M
EPS estimate-$0.42

Financials

Q2 2025

Income statement

See full
Revenue$119.0K-67.8%
Operating income-$29.0M-60.4%
Net income-$24.8M-50.4%
EPS (diluted)-$0.56+92.0%

Balance sheet

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Cash & equivalents$189.3M+44.3%
Total debt$24.6M—
Total equity$377.6M+657%
Total assets$415.2M—

Cash flow

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Operating cash flow-$20.3M-56.2%
CapEx$58.0K-61.1%
Free cash flow-$20.3M-54.9%

Valuation & ratios

Valuation

as of 06/30/25
See full
Market cap$477.22M—
Enterprise value$312.48M—
P/S657.3×—

Profitability

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Operating margin-14,071.1%-15,735pp
Net margin-12,053%-12,968pp
FCF margin-11,436.9%—

Returns & leverage

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Debt / equity0.1×—
Current ratio22.1×—

FAQ

When did Septerna, Inc. report Q2 2025 earnings?
Septerna, Inc. (SEPN) reported Q2 2025 earnings on August 11, 2025 before market open.
What were Septerna, Inc.'s Q2 2025 revenue and EPS?
Septerna, Inc. reported revenue of $119.0K and eps of $-0.56 for Q2 2025.
Did Septerna, Inc. beat estimates in Q2 2025?
Revenue missed the consensus estimate of $5.0M by $4.9M. EPS missed the consensus estimate of $-0.05 by $0.51.
Where can I find Septerna, Inc.'s Q2 2025 SEC filings?
You can read the 8-K earnings release (0000950170-25-106540) and the 10-Q periodic report (0000950170-25-106551) directly on SEC EDGAR. The filing index links above go to sec.gov.