What is Upstream Bio, Inc.'s debt-to-assets?

Upstream Bio, Inc. (UPB) reported debt-to-assets of 0× in Q1 2026.

How has Upstream Bio, Inc.'s debt-to-assets changed year-over-year?

Upstream Bio, Inc.'s debt-to-assets decreased by 5.4% year-over-year, from 0× to 0×.

What is the long-term trend for Upstream Bio, Inc.'s debt-to-assets?

Over 2 years (2023 to 2025), Upstream Bio, Inc.'s debt-to-assets has grown at a 200.0% compound annual growth rate (CAGR), from 0× to 0×.

What does debt-to-assets mean?

Total debt divided by total assets at the quarter end. Measures the share of the asset base financed by debt.

Upstream Bio, Inc. UPB Debt-to-assets

Debt-to-assets at other companies

AmgenAMGN

0.6×0.0×

Regeneron PharmaceuticalsREGN

0.1×0.0×

Aclaris TherapeuticsACRS

0×0.0×

Shattuck Labs, Inc.STTK

0×0.0×

SavaraSVRA

0.1×0.0×

AnaptysBio, Inc.ANAB

0×—

Other financials

Income statement

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Revenue$1.0M+82.7%

Operating income-$43.6M-36.2%

Net income-$40.6M-48.8%

EPS (diluted)-$0.75-47.1%

Balance sheet

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Cash & equivalents$96.7M+35.6%

Total debt$1.1M-34.5%

Total equity$304.0M-31.8%

Total assets$318.1M-30.3%

Cash flow

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Operating cash flow-$47.9M-16.2%

CapEx$54.0K-70.8%

Free cash flow-$30.7M-55.0%

Valuation

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Market cap$346.11M-40.9%

Enterprise value$250.5M-51.4%

P/S104.2×-151×

Profitability

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Operating margin-5,176.5%+1,764pp

Net margin-4,719%+2,752pp

Returns & leverage

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Return on equity-41.8%—

Debt / equity0×0.0×

Current ratio23.1×-24.3×

Where this comes from

Calculated from Upstream Bio, Inc.’s reported figures.

total debt/total assets=0×

Based on the most recent quarter.

The official record: Upstream Bio, Inc.’s 10-Q, filed May 13, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Upstream Bio, Inc.'s debt-to-assets?: Upstream Bio, Inc. (UPB) reported debt-to-assets of 0× in Q1 2026.
How has Upstream Bio, Inc.'s debt-to-assets changed year-over-year?: Upstream Bio, Inc.'s debt-to-assets decreased by 5.4% year-over-year, from 0× to 0×.
What is the long-term trend for Upstream Bio, Inc.'s debt-to-assets?: Over 2 years (2023 to 2025), Upstream Bio, Inc.'s debt-to-assets has grown at a 200.0% compound annual growth rate (CAGR), from 0× to 0×.
What does debt-to-assets mean?: Total debt divided by total assets at the quarter end. Measures the share of the asset base financed by debt.