When did Septerna, Inc. report Q1 2025 earnings?

Septerna, Inc. (SEPN) reported Q1 2025 earnings on May 15, 2025 before market open.

What were Septerna, Inc.'s Q1 2025 revenue and EPS?

Septerna, Inc. reported revenue of $219.0K and diluted EPS of $-0.49 for Q1 2025.

Did Septerna, Inc. beat estimates in Q1 2025?

Revenue missed the consensus estimate of $30.0M by $29.8M. EPS missed the consensus estimate of $-0.38 by $0.11.

Where can I find Septerna, Inc.'s Q1 2025 SEC filings?

You can read the 10-Q periodic report (0000950170-25-072619) directly on SEC EDGAR. The filing index links above go to sec.gov.

Septerna, Inc. SEPN Q1 2025 earnings

Reported May 15, 2025 · Before market open

Revenue$219.0KMiss by $29.8M Diluted EPS-$0.49Miss by $0.11

Revenue estimate$30.0M

EPS estimate-$0.38

Next report

Aug 10, 2026 (In 4 weeks)

Revenue estimate$19.2M

EPS estimate-$0.48

Financials

Q1 2025

Income statement

See full

Revenue$219.0K-30.9%

Operating income-$25.9M-67.3%

Net income-$21.5M-52.3%

EPS (diluted)-$0.49+92.3%

Balance sheet

See full

Cash & equivalents$210.0M+158%

Total debt$25.0M—

Total equity-$400.3M-671%

Total assets$434.0M—

Cash flow

See full

Operating cash flow-$23.3M-39.7%

CapEx$382.0K-50.0%

Free cash flow-$23.7M-35.8%

Valuation & ratios

Valuation

as of 03/31/25

See full

Market cap$257.32M—

Enterprise value$72.3M—

P/S263.4×—

Profitability

See full

Operating margin-9,339.1%—

Net margin-8,104.1%—

FCF margin-7,760.8%—

Returns & leverage

See full

Current ratio32.2×—

Versus estimates

Revenue

Q1 2026$26.5MBeat by $9.5M Q4 2025$24.1MBeat by $5.9M Q3 2025$21.5MBeat by $4.2M Q2 2025$119.0KMiss by $4.9M

Q1 2025$219.0KMiss by $29.8M

Q4 2024$212.0K

Diluted EPS

Q1 2026-$0.19Beat by $0.32 Q4 2025-$0.24Miss by $0.01 Q3 2025-$0.09Miss by $0.28 Q2 2025-$0.56Miss by $0.51

Q1 2025-$0.49Miss by $0.11

Q4 2024-$0.64Beat by $0.05

Ask the moment Septerna, Inc. reports.

Connect your AI and ask the moment the filing drops. It reads the release, surfaces what management said, and gives you its own read.

Connect your AI

Claude

Questions, answered.

When did Septerna, Inc. report Q1 2025 earnings?: Septerna, Inc. (SEPN) reported Q1 2025 earnings on May 15, 2025 before market open.
What were Septerna, Inc.'s Q1 2025 revenue and EPS?: Septerna, Inc. reported revenue of $219.0K and diluted EPS of $-0.49 for Q1 2025.
Did Septerna, Inc. beat estimates in Q1 2025?: Revenue missed the consensus estimate of $30.0M by $29.8M. EPS missed the consensus estimate of $-0.38 by $0.11.
Where can I find Septerna, Inc.'s Q1 2025 SEC filings?: You can read the 10-Q periodic report (0000950170-25-072619) directly on SEC EDGAR. The filing index links above go to sec.gov.