When did Upstream Bio, Inc. report Q4 2024 earnings?

Upstream Bio, Inc. (UPB) reported Q4 2024 earnings on March 13, 2025 before market open.

What were Upstream Bio, Inc.'s Q4 2024 revenue and EPS?

Upstream Bio, Inc. reported revenue of $613.0K and diluted EPS of $-1.59 for Q4 2024.

Did Upstream Bio, Inc. beat estimates in Q4 2024?

Revenue beat the consensus estimate of $326.3K by $286.8K. EPS missed the consensus estimate of $-0.56 by $1.03.

Where can I find Upstream Bio, Inc.'s Q4 2024 SEC filings?

You can read the 10-K periodic report (0000950170-25-037621) directly on SEC EDGAR. The filing index links above go to sec.gov.

Upstream Bio, Inc. UPB Q4 2024 Annual earnings

Reported March 13, 2025 · Before market open

Revenue$613.0KBeat by $286.8K Diluted EPS-$1.59Miss by $1.03

Revenue estimate$326.3K

EPS estimate-$0.56

Next report

Aug 5, 2026 (In 3 weeks)

Revenue estimate$431.1K

EPS estimate-$0.78

Financials

Q4 2024

Income statement

See full

Revenue$613.0K+36.2%

Operating income-$26.3M-83.7%

Net income-$21.2M-79.5%

Balance sheet

See full

Cash & equivalents$325.9M+1,162%

Total debt$1.8M+3,976%

Total equity$469.9M+482%

Total assets$481.7M+311%

Cash flow

See full

Operating cash flow-$19.6M-21.7%

CapEx$185.0K+414%

Free cash flow-$19.8M-22.9%

Valuation & ratios

Valuation

as of 12/31/24

See full

Market cap$881.13M—

Enterprise value$557.07M—

P/S371.8×—

Profitability

See full

Operating margin-3,281.2%—

Net margin-2,650%—

Returns & leverage

See full

Debt / equity0×—

Current ratio44.6×+26.7×

Versus estimates

Revenue

Q1 2026$1.0MBeat by $6.3K Q4 2025$668.0KBeat by $84.0K Q3 2025$683.0KBeat by $161.4K Q2 2025$937.0KBeat by $620.0K Q1 2025$566.0KBeat by $249.0K

Q4 2024$613.0KBeat by $286.8K

Diluted EPS

Q1 2026-$0.75Miss by $0.01 Q4 2025-$0.79Miss by $0.06 Q3 2025-$0.63Beat by $0.15 Q2 2025-$0.74Miss by $0.13 Q1 2025-$0.51Miss by $0.02

Q4 2024-$1.59Miss by $1.03

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Questions, answered.

When did Upstream Bio, Inc. report Q4 2024 earnings?: Upstream Bio, Inc. (UPB) reported Q4 2024 earnings on March 13, 2025 before market open.
What were Upstream Bio, Inc.'s Q4 2024 revenue and EPS?: Upstream Bio, Inc. reported revenue of $613.0K and diluted EPS of $-1.59 for Q4 2024.
Did Upstream Bio, Inc. beat estimates in Q4 2024?: Revenue beat the consensus estimate of $326.3K by $286.8K. EPS missed the consensus estimate of $-0.56 by $1.03.
Where can I find Upstream Bio, Inc.'s Q4 2024 SEC filings?: You can read the 10-K periodic report (0000950170-25-037621) directly on SEC EDGAR. The filing index links above go to sec.gov.