What is Upstream Bio, Inc.'s change in lease liabilities?

Upstream Bio, Inc. (UPB) reported change in lease liabilities of -$155K in Q1 2026.

How has Upstream Bio, Inc.'s change in lease liabilities changed year-over-year?

Upstream Bio, Inc.'s change in lease liabilities decreased by 15.7% year-over-year, from -$134K to -$155K.

What does change in lease liabilities mean?

Cash payments for operating leases reducing the lease liability, partially offset by new lease commencements.

Upstream Bio, Inc. UPB Change in Lease Liabilities

Change in Lease Liabilities at other companies

Shattuck Labs, Inc.STTK

-$225K+6.3%

AnaptysBio, Inc.ANAB

-$499K-8.0%

Theravance BiopharmaTBPH

-$2.2M-32.2%

Ethos Technologies, Inc. LIFE

-$191K-17.9%

MoonLake ImmunotherapeuticsMLTX

-$389K-52.5%

Septerna, Inc.SEPN

-$535K-18.9%

Other financials

Income statement

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Revenue$1.0M+82.7%

Operating income-$43.6M-36.2%

Net income-$40.6M-48.8%

EPS (diluted)-$0.75-47.1%

Balance sheet

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Cash & equivalents$96.7M+35.6%

Total debt$1.1M-34.5%

Total equity$304.0M-31.8%

Total assets$318.1M-30.3%

Cash flow

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Operating cash flow-$47.9M-16.2%

CapEx$54.0K-70.8%

Free cash flow-$30.7M-55.0%

Valuation

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Market cap$346.11M-40.9%

Enterprise value$250.5M-51.4%

P/S104.2×-151×

Profitability

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Operating margin-5,176.5%+1,764pp

Net margin-4,719%+2,752pp

Returns & leverage

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Return on equity-41.8%—

Debt / equity0×0.0×

Current ratio23.1×-24.3×

Where this comes from

Reported directly by Upstream Bio, Inc. in its filing.

Tagged under the XBRL concept us-gaap:IncreaseDecreaseInOperatingLeaseLiability.

The official record: Upstream Bio, Inc.’s 10-Q, filed May 13, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Upstream Bio, Inc.'s change in lease liabilities?: Upstream Bio, Inc. (UPB) reported change in lease liabilities of -$155K in Q1 2026.
How has Upstream Bio, Inc.'s change in lease liabilities changed year-over-year?: Upstream Bio, Inc.'s change in lease liabilities decreased by 15.7% year-over-year, from -$134K to -$155K.
What does change in lease liabilities mean?: Cash payments for operating leases reducing the lease liability, partially offset by new lease commencements.