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Spyre Therapeutics, Inc. SYRE AFS and Trading Securities - Unrealized Loss Position (>=12 Months) Accumulated Loss

AFS and Trading Securities - Unrealized Loss Position (>=12 Months) Accumulated Loss at other companies

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Ionis PharmaceuticalsIONS
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Other financials

Income statement

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Revenue-—
Operating income-$45.6M+14.8%
Net income-$69.0M-54.1%
EPS (diluted)-$0.74-23.3%

Balance sheet

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Cash & equivalents$97.2M+100%
Total debt$4.3M-9.6%
Total equity$670.8M+39.0%
Total assets$764.0M+34.1%

Cash flow

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Operating cash flow-$57.4M-40.0%
CapEx-—
Free cash flow-$39.4M-26.8%

Valuation

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Market cap$7.67B+307%

Profitability

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Operating margin-39,428.9%-49,795pp
Net margin-52,939.7%-61,871pp
FCF margin-3,442.8%-3,807pp

Returns & leverage

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Return on equity-31.1%-10.7pp
Debt / equity0.1×+0.1×
Current ratio9×+0.9×

Where this comes from

Reported directly by Spyre Therapeutics, Inc. in its filing.

Tagged under the XBRL concept us-gaap:DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPosition12MonthsOrLongerAccumulatedLoss.

The official record: Spyre Therapeutics, Inc.’s 10-Q, filed May 5, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Spyre Therapeutics, Inc.'s AFS and trading securities - unrealized loss position (>=12 months) accumulated loss?
Spyre Therapeutics, Inc. (SYRE) reported AFS and trading securities - unrealized loss position (>=12 months) accumulated loss of $0 in Q1 2026.