What is Spyre Therapeutics, Inc.'s due in 1 - 2 years?

Spyre Therapeutics, Inc. (SYRE) reported due in 1 - 2 years of $225.08M in Q1 2026.

How has Spyre Therapeutics, Inc.'s due in 1 - 2 years changed year-over-year?

Spyre Therapeutics, Inc.'s due in 1 - 2 years increased by 50.8% year-over-year, from $149.22M to $225.08M.

What is the long-term trend for Spyre Therapeutics, Inc.'s due in 1 - 2 years?

Over 2 years (2023 to 2025), Spyre Therapeutics, Inc.'s due in 1 - 2 years has grown at a 157.8% compound annual growth rate (CAGR), from $34.6M to $229.92M.

Spyre Therapeutics, Inc. SYRE Due in 1 - 2 years

Other financials

Income statement

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Revenue-—

Operating income-$45.6M+14.8%

Net income-$69.0M-54.1%

EPS (diluted)-$0.74-23.3%

Balance sheet

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Cash & equivalents$97.2M+100%

Total debt$4.3M-9.6%

Total equity$670.8M+39.0%

Total assets$764.0M+34.1%

Cash flow

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Operating cash flow-$57.4M-40.0%

CapEx-—

Free cash flow-$39.4M-26.8%

Valuation

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Market cap$7.67B+307%

Profitability

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Operating margin-39,428.9%-49,795pp

Net margin-52,939.7%-61,871pp

FCF margin-3,442.8%-3,807pp

Returns & leverage

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Return on equity-31.1%-10.7pp

Debt / equity0.1×+0.1×

Current ratio9×+0.9×

Where this comes from

Reported directly by Spyre Therapeutics, Inc. in its filing.

Tagged under the XBRL concept syre:DebtSecuritiesAvailableForSaleFairValueMaturityAllocatedAndSingleMaturityDateAfterYearOne.

The official record: Spyre Therapeutics, Inc.’s 10-Q, filed May 5, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Spyre Therapeutics, Inc.'s due in 1 - 2 years?: Spyre Therapeutics, Inc. (SYRE) reported due in 1 - 2 years of $225.08M in Q1 2026.
How has Spyre Therapeutics, Inc.'s due in 1 - 2 years changed year-over-year?: Spyre Therapeutics, Inc.'s due in 1 - 2 years increased by 50.8% year-over-year, from $149.22M to $225.08M.
What is the long-term trend for Spyre Therapeutics, Inc.'s due in 1 - 2 years?: Over 2 years (2023 to 2025), Spyre Therapeutics, Inc.'s due in 1 - 2 years has grown at a 157.8% compound annual growth rate (CAGR), from $34.6M to $229.92M.